Clear light yellow colored antibiotic solution containing 300mg florphenicol in each ml.

Florphenicol is a thiamphenicol derivation, containing fluorine group in its chemical structure instead of hydroxyl bonded to 3 staged carbon atom. Florphenicol has bactericidal effect. It inhibits the protein synthesis by binding to the 50S ribosomal subunits of bacteria.
THE MAIN SENSITIVE BACTERIA ARE AS FOLLOWS:
Gram positive bacteria: Actinomyces sp. Corynebacterium sp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, most of Staphylococcus sp. and Streptococcus sp.
Gram negative bacteria: Actinobacillus sp., Bordetella bronchiseptica, Enterobacteriaceae (E.coli, Klebsiella sp., Proteus sp., Salmonella sp.), Haemophilus sp., Leptospira sp., Moraxella sp., Pasteurella sp.
All anaerobes are generally sensitive.
When drug is orally administered, it is quickly absorbed through digestion system and distributed through body tissues via blood circulation. At the tests held in excretion and urine after the administration of 20mg/kg live weight dose, 97% is eliminated through urination and the remaining amount is eliminated through excretion. In urine 52% is eliminated unchanged, 25% is eliminated as oxamic acid.

Bio-phenicol Oral Solution is used in broiler chickens to treat respiration tract diseases caused by E.coli, sacculitis and coli septicemia.

Florphenicol is used by adding into drinking water for 3-5 days on 30mg/kg live weight basis. Practical dose is 100m1 Bio-phenicol Oral solution for every 1000kg depending on the water consumption.

It is sold at veterinary clinics and pharmacies with veterinarian prescription. (VHR- Veterinary Doctor Prescription)